| Document ID (ISN) | 19647 |
| CIS number |
72-2477 |
| ISSN - Serial title |
0032-6291 - Pracovní lékařství |
| Year |
1972 |
| Convention or series no. |
|
| Author(s) |
Cramér K., Selander S. |
| Title |
Comparison between D-penicillamine and N-acetyl-D-penicillamine in the treatment of lead poisoning |
| Bibliographic information |
Mar. 1972, Vol.24, No.2-3, p.46-48. Illus. 7 ref. |
| Abstract |
D-Penicillamine and N-acetyl-D-penicillamine were compared in the treatment of 2 workers with excessive lead absorption. The acetylated compound did not produce any significant increase in urinary lead; the non-acetylated compound had a satisfactory chelating action and produced an immediate reduction in urinary concentration and 24-h elimination of δ-aminolevulinic acid. The existence of a free amino group is essential for the chelating of D-penicillamine. |
| Descriptors (primary) |
lead; chelation therapy; chronic poisoning; toxicology |
| Descriptors (secondary) |
ALAD; urinary ala monitoring; shipbreaking; penicillamine |
| Document type |
D - Periodical articles |
| Subject(s) |
Medicine, hygiene and first aid
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Inorganic substances
Shipwrecking
Lead and compounds
|
