| Document ID (ISN) | 27173 |
| CIS number |
77-791 |
| ISSN - Serial title |
0016-9900 - Gigiena i sanitarija |
| Year |
1976 |
| Convention or series no. |
|
| Author(s) |
Beljaeva N.N., Bystrova T.A., Revazova Ju.A., Arhangel'skij V.I. |
| Title |
Comparative evaluation of the toxic and mutagenic properties of organic tin compounds |
| Original title |
Sravnitel'naja ocenka toksičeskih i mutagennyh svojstv organičeskih soedinenij olova [in Russian] |
| Bibliographic information |
May 1976, No.5, p.10-14. 7 ref. |
| Abstract |
Bis(tributyltin)oxide (BTO), butyltin trilaurate (BTT) and dibutyltin bis(trifluoroacetate) (DTBT) were administered to mice by ingestion and inhalation. Results for LD50, GOT and GPT inhibition, cholinesterase activation, frequency and nature of chromosome aberrations) are given. DTBT and BTO were more toxic than BTT. All possessed marked cumulative properties which increased in inverse proportion to the daily dose. |
| Descriptors (primary) |
mutagenic effects; toxicology; organotin compounds |
| Descriptors (secondary) |
dibutyltin bis(trifluoroacetate); butyltin trilaurate; vulcanization accelerators; stabilizers; enzyme disturbances; comparative study; toxicity evaluation; animal experiments; chromosome changes; cumulative properties; tributyltin oxide; fungicides |
| Document type |
- |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Genetic factors in reaction to exposures
Antifertility and prenatal effects
|
