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CISDOC database

Document ID (ISN)30249
CIS number 78-1931
Year 1978
Convention or series no.
Author(s) Lagneau C.
Title Bladder cancer and dye manufacture
Original title Lésions vésicales et fabrication des colorants. [in French]
Bibliographic information Université de Paris V, Faculté de médecine Necker - Enfants Malades, Paris, France, 1978. 93p. 61 ref.
Abstract MD thesis. History of bladder tumours in the dye industry and incidence in France, USA, United Kingdom, Italy, USSR. Review of known bladder carcinogens (1- and 2-naphthylamine, benzidine, 4-aminobiphenyl or p-xenylamine and auramine) and probable carcinogens (o-dianisidine, 3,-3'-dichlorobenzidine, magenta, 2,3'-dimethylazobenzene, o-aminoazotoluene, acetylaminofluorene, 3,3'-dihydroxybenzidine, p-nitrobiphenyl). General remarks and review of chief theories of carcinogesis. Early diagnosis of occupational bladder cancer (microhaematuria, urinary cytology, routine cystoscopy). Report of various forms and stages of the pathological process, with concrete case histories. Prevention measures in dye production plant: enclosure; high ceilings to facilitate ventilation; walls impervious to carcinogens; regular washing of floors; prohibition of 2-naphthylamine (USSR and United Kingdom); handling of benzidine in paste form; protective clothing; showers after work. Hazards and their prevention at different production stages. French compensation system.
Descriptors (primary) carcinogens; dyestuff industry; bladder tumour; dyes
Descriptors (secondary) protective clothing; prohibition of use; France; auramine OAF; 1-naphthylamine; 4-aminobiphenyl; 4-nitrobiphenyl; 2-acetylaminofluorene; dimethoxybenzidine; 3,3'-dihydroxybenzidine; 2-naphthylamine; 3,3'-dichlorobenzidine; 4-amino-2',3-dimethylazobenzene; early diagnosis; Magenta; thesis; health engineering; personal hygiene; enclosure; ventilation; urine cytology; history; benzidine; compensation of occupational diseases
Document type E - Books, reports, proceedings
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Diseases of the kidney and the urinary system
Chemical industry