| Document ID (ISN) | 35632 |
| CIS number |
81-1007 |
| ISSN - Serial title |
Gigiena truda i professional'nye zabolevanija |
| Year |
1980 |
| Convention or series no. |
|
| Author(s) |
Pastušenko T.V., Manenko A.K. |
| Title |
Establishment of a TLV for pentachloroacetophenone in workplace air |
| Original title |
Obosnovanie predel'no dopustimoj koncentracii pentahloracetofenona v vozduhe rabočej zony [in Russian] |
| Bibliographic information |
Mar. 1980, No.3, p.48-49. 2 ref. |
| Abstract |
LD50 for this substance, an intermediate in the synthesis of vinyl phosphate insecticide, is 1,250mg/kg for rats and 700mg/kg for mice (intragastric administration). The compound has marked percutaneous toxicity (LD50 at 1,800mg/kg), irritates the skin and mucosae, and has a marked tendency to accumulate in the body. TLVs established were: 77mg/m3 (acute effects); 28mg/m3 (chronic effects); and 2.7mg/m3 (chronic effect range). Recommended TLV for workplace air: 3mg/m3 with warning "cutaneous absorption". |
| Descriptors (primary) |
threshold limit values; pesticide production; pentachloroacetophenone; USSR |
| Descriptors (secondary) |
irritation; cumulative properties; animal experiments; skin absorption |
| Document type |
D - Periodical articles |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Chemical industry
Occupational exposure limits
Ketones
|
