| Document ID (ISN) | 36550 |
| CIS number |
81-1937 |
| ISSN - Serial title |
Gigiena truda i professional'nye zabolevanija |
| Year |
1980 |
| Convention or series no. |
|
| Author(s) |
Sidorin G.I., Tkačuk G.N., Frolova A.D., Šavkunov S.A. |
| Title |
Experimental establishment of a maximum allowable concentration of nitroacetic acid methyl and ethyl esters |
| Original title |
Ėksperimental'noe obosnovanie predel'no dopustimoj koncentracii metilovogo i ėtilovogo ėfirov nitrouksusnoj kisloty [in Russian] |
| Bibliographic information |
July 1980, No.7, p.49-51. 2 ref. |
| Abstract |
Methyl nitroacetate (MNA) and ethyl nitroacetate (ENA) are used in the synthesis of certain amino acids. Animal studies have shown that MNA is extremely harmful on long-term exposure, that it accumulates in the body and has a wide spectrum of chronic effects. The closeness of the thresholds for general toxic action and for specific action suggest the adoption of a threshold limit value of 2mg/m3 for MNA. The similarity between the physical and chemical properties of the 2 substances, their acute toxicity, their accumulation coefficient and their thresholds of action following one-time administration place the 2 substances in the same hazard class; however, since ENA has a slightly lower acute toxicity, its recommended threshold limit value is 5mg/m3. |
| Descriptors (primary) |
threshold limit values; methyl nitroacetate; ethyl nitroacetate; USSR |
| Descriptors (secondary) |
animal experiments |
| Document type |
D - Periodical articles |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Occupational exposure limits
Esters and salts
|
