| Document ID (ISN) | 40159 |
| CIS number |
83-1367 |
| ISSN - Serial title |
Gigiena truda i professional'nye zabolevanija |
| Year |
1981 |
| Convention or series no. |
|
| Author(s) |
Timošenko L.V., Volodčenko V.A., Danilov V.I., Ševcov V.E., Ostrovskaja I.S. |
| Title |
Experimental determination of the threshold limit value for dibromobenzanthrone |
| Original title |
Materialy k ėksperimental'nomu obosnovaniju predel'no dopustimoj koncentracii dibrombenzantrona [in Russian] |
| Bibliographic information |
June 1981, No.6, p.51-52. 10 ref. |
| Abstract |
Dibromobenzanthrone (DDB), an intermediate in dye manufacture, was administered to rats, mice and rabbits by intraperitoneal, inhalation and intragastric routes at a dose equal to one-half the LD50 over various time periods. The low volatility of DDB and its relatively low acute toxicity indicate that the probability of acute poisoning in the workplace is low, but since the effects of the compound (blood abnormalities and enlargement of internal organs) are cumulative, the compound should be considered hazardous. A TLV of 0.2mg/m3 is recommended |
| Descriptors (primary) |
threshold limit values; toxicology; dibromobenzanthrone; USSR |
| Descriptors (secondary) |
hepatotoxic effects; splenomegaly; dyes; dyestuff industry; haematotoxic effects; nephrotoxic effects; animal experiments |
| Document type |
D - Periodical articles |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
|
| Browse category(ies) |
Occupational exposure limits
Ketones
|
