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CISDOC database
| Document ID (ISN) | 42593 |
| CIS number |
84-1668 |
| ISSN - Serial title |
0098-4108 - Journal of Toxicology and Environmental Health |
| Year |
1983 |
| Convention or series no. |
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| Author(s) |
Miller T.L., Lorusso D.J., Walsh M.L., Deinzer M.L. |
| Title |
The acute toxicity of penta-, hexa-, and heptachlorohydroxydiphenyl ethers in mice |
| Bibliographic information |
Aug.-Sep. 1983, Vol.12, Nos. 2-3, p.245-253. Illus. 23 ref. |
| Abstract |
The acute intraperitoneal LD50 values determined for a series of polychlorohydroxydiphenyl ethers (Cl=5-7) were slightly less than those found for Irgasan DP-300 and substantially less than those observed for nonachlorohydroxydiphenyl ether and pentachlorophenol. A marked hypothermic effect was found, and symptomatology suggested a non-specific depressant effect on the central nervous system. |
| Descriptors (primary) |
chlorophenols; toxicology |
| Descriptors (secondary) |
4,5-dichloro-2-(2,3,5,6-tetrachlorophenoxy)-phenol; central nervous system; acute toxicity; pentachlorophenol; 2-(pentachlorophenoxy)phenol; 4,5-dichloro-2-(pentachlorophenoxy)-phenol; 4-(pentachlorophenoxy)phenol; 2,3,4-trichloro-6-(2,4-dichlorophenoxy)phenol; 4,5-dichloro-2-(2,4,5-trichlorophenoxy)-phenol; animal experiments; lethal dose 50; 3-(pentachlorophenoxy)phenol |
| Document type |
D - Periodical articles |
| Subject(s) |
Occupational pathology
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| Broad subject area(s) |
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| Browse category(ies) |
Phenols and phenolic compounds
Alcohols
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